Found 36 hits of ic50 data for complexid = 50025409 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481474
(CHEMBL603465)Show SMILES Clc1ccccc1C(N1CCN(CC1)C(=O)NC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H30ClN3O/c32-28-19-11-10-18-27(28)30(26-16-8-3-9-17-26)34-20-22-35(23-21-34)31(36)33-29(24-12-4-1-5-13-24)25-14-6-2-7-15-25/h1-19,29-30H,20-23H2,(H,33,36) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481454
(CHEMBL596942)Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)NC(c2ccccc2)c2ccccc2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C31H29Cl2N3O/c32-26-16-17-27(28(33)22-26)30(25-14-8-3-9-15-25)35-18-20-36(21-19-35)31(37)34-29(23-10-4-1-5-11-23)24-12-6-2-7-13-24/h1-17,22,29-30H,18-21H2,(H,34,37) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481448
(CHEMBL605965)Show SMILES Clc1ccccc1C(N1CCN(CC(=O)N(c2ccccc2)c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C31H30ClN3O/c32-29-19-11-10-18-28(29)31(25-12-4-1-5-13-25)34-22-20-33(21-23-34)24-30(36)35(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-19,31H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481469
(CHEMBL597969)Show SMILES Fc1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H31FN2O/c33-29-18-16-28(17-19-29)32(27-14-8-3-9-15-27)35-22-20-34(21-23-35)31(36)24-30(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-19,30,32H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481487
(CHEMBL598392)Show SMILES Clc1cccc(c1)C(N1CCN(CC(=O)N(c2ccccc2)c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C31H30ClN3O/c32-27-14-10-13-26(23-27)31(25-11-4-1-5-12-25)34-21-19-33(20-22-34)24-30(36)35(28-15-6-2-7-16-28)29-17-8-3-9-18-29/h1-18,23,31H,19-22,24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481483
(CHEMBL589285)Show SMILES COc1cc(cc(OC)c1OC)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H38N2O4/c1-39-31-23-29(24-32(40-2)35(31)41-3)34(28-17-11-6-12-18-28)37-21-19-36(20-22-37)33(38)25-30(26-13-7-4-8-14-26)27-15-9-5-10-16-27/h4-18,23-24,30,34H,19-22,25H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481449
(CHEMBL599408)Show SMILES O=C(CN1CCN(CC1)C(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-30(34(28-17-9-3-10-18-28)29-19-11-4-12-20-29)25-32-21-23-33(24-22-32)31(26-13-5-1-6-14-26)27-15-7-2-8-16-27/h1-20,31H,21-25H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481468
(CHEMBL606175)Show SMILES COc1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H34N2O2/c1-37-30-19-17-29(18-20-30)33(28-15-9-4-10-16-28)35-23-21-34(22-24-35)32(36)25-31(26-11-5-2-6-12-26)27-13-7-3-8-14-27/h2-20,31,33H,21-25H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481486
(CHEMBL597788)Show SMILES FC(F)(F)c1cccc(c1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H31F3N2O/c34-33(35,36)29-18-10-17-28(23-29)32(27-15-8-3-9-16-27)38-21-19-37(20-22-38)31(39)24-30(25-11-4-1-5-12-25)26-13-6-2-7-14-26/h1-18,23,30,32H,19-22,24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481466
(CHEMBL599217)Show SMILES O=C(NC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-31(32-29(25-13-5-1-6-14-25)26-15-7-2-8-16-26)34-23-21-33(22-24-34)30(27-17-9-3-10-18-27)28-19-11-4-12-20-28/h1-20,29-30H,21-24H2,(H,32,35) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481488
(CHEMBL597970)Show SMILES Cc1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H34N2O/c1-26-17-19-30(20-18-26)33(29-15-9-4-10-16-29)35-23-21-34(22-24-35)32(36)25-31(27-11-5-2-6-12-27)28-13-7-3-8-14-28/h2-20,31,33H,21-25H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481447
(CHEMBL598598)Show SMILES Clc1ccc(cc1)C(N1CCN(CC(=O)N(c2ccccc2)c2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C31H30ClN3O/c32-27-18-16-26(17-19-27)31(25-10-4-1-5-11-25)34-22-20-33(21-23-34)24-30(36)35(28-12-6-2-7-13-28)29-14-8-3-9-15-29/h1-19,31H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481467
(CHEMBL598603)Show SMILES COc1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccc(OC)cc1 Show InChI InChI=1S/C34H36N2O3/c1-38-30-17-13-28(14-18-30)34(29-15-19-31(39-2)20-16-29)36-23-21-35(22-24-36)33(37)25-32(26-9-5-3-6-10-26)27-11-7-4-8-12-27/h3-20,32,34H,21-25H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481462
(CHEMBL597782)Show SMILES CN1CCC(CC1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C32H38ClN3O/c1-34-18-16-28(17-19-34)32(27-12-14-29(33)15-13-27)36-22-20-35(21-23-36)31(37)24-30(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-15,28,30,32H,16-24H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481466
(CHEMBL599217)Show SMILES O=C(NC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-31(32-29(25-13-5-1-6-14-25)26-15-7-2-8-16-26)34-23-21-33(22-24-34)30(27-17-9-3-10-18-27)28-19-11-4-12-20-28/h1-20,29-30H,21-24H2,(H,32,35) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481464
(CHEMBL599625)Show SMILES Cc1ccc(C(N2CCN(CC(=O)N(c3ccccc3)c3ccccc3)CC2)c2ccccc2)c(C)c1 Show InChI InChI=1S/C33H35N3O/c1-26-18-19-31(27(2)24-26)33(28-12-6-3-7-13-28)35-22-20-34(21-23-35)25-32(37)36(29-14-8-4-9-15-29)30-16-10-5-11-17-30/h3-19,24,33H,20-23,25H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481477
(CHEMBL599402)Show SMILES Clc1ccc(cc1)[C@H](N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C32H31ClN2O/c33-29-18-16-28(17-19-29)32(27-14-8-3-9-15-27)35-22-20-34(21-23-35)31(36)24-30(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-19,30,32H,20-24H2/t32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481472
(CHEMBL597585)Show SMILES FC(F)(F)c1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H31F3N2O/c34-33(35,36)29-18-16-28(17-19-29)32(27-14-8-3-9-15-27)38-22-20-37(21-23-38)31(39)24-30(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-19,30,32H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481476
(CHEMBL599404)Show SMILES Clc1cccc(c1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H31ClN2O/c33-29-18-10-17-28(23-29)32(27-15-8-3-9-16-27)35-21-19-34(20-22-35)31(36)24-30(25-11-4-1-5-12-25)26-13-6-2-7-14-26/h1-18,23,30,32H,19-22,24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481486
(CHEMBL597788)Show SMILES FC(F)(F)c1cccc(c1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H31F3N2O/c34-33(35,36)29-18-10-17-28(23-29)32(27-15-8-3-9-16-27)38-21-19-37(20-22-38)31(39)24-30(25-11-4-1-5-12-25)26-13-6-2-7-14-26/h1-18,23,30,32H,19-22,24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481484
(CHEMBL599403)Show SMILES Clc1ccc(cc1)[C@@H](N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C32H31ClN2O/c33-29-18-16-28(17-19-29)32(27-14-8-3-9-15-27)35-22-20-34(21-23-35)31(36)24-30(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-19,30,32H,20-24H2/t32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481477
(CHEMBL599402)Show SMILES Clc1ccc(cc1)[C@H](N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C32H31ClN2O/c33-29-18-16-28(17-19-29)32(27-14-8-3-9-15-27)35-22-20-34(21-23-35)31(36)24-30(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-19,30,32H,20-24H2/t32-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481470
(CHEMBL596946)Show SMILES Clc1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H31ClN2O/c33-29-18-16-28(17-19-29)32(27-14-8-3-9-15-27)35-22-20-34(21-23-35)31(36)24-30(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-19,30,32H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481465
(CHEMBL597572)Show SMILES Clc1cccc(C(N2CCN(CC(=O)N(c3ccccc3)c3ccccc3)CC2)c2ccccc2)c1Cl Show InChI InChI=1S/C31H29Cl2N3O/c32-28-18-10-17-27(30(28)33)31(24-11-4-1-5-12-24)35-21-19-34(20-22-35)23-29(37)36(25-13-6-2-7-14-25)26-15-8-3-9-16-26/h1-18,31H,19-23H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481476
(CHEMBL599404)Show SMILES Clc1cccc(c1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H31ClN2O/c33-29-18-10-17-28(23-29)32(27-15-8-3-9-16-27)35-21-19-34(20-22-35)31(36)24-30(25-11-4-1-5-12-25)26-13-6-2-7-14-26/h1-18,23,30,32H,19-22,24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481481
(CHEMBL597775)Show SMILES Clc1ccc(C(N2CCN(CC(=O)N(c3ccccc3)c3ccccc3)CC2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C31H29Cl2N3O/c32-25-16-17-28(29(33)22-25)31(24-10-4-1-5-11-24)35-20-18-34(19-21-35)23-30(37)36(26-12-6-2-7-13-26)27-14-8-3-9-15-27/h1-17,22,31H,18-21,23H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481463
(CHEMBL605769)Show SMILES CN1CCCC(C1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H39N3O/c1-33-19-11-18-29(25-33)32(28-16-9-4-10-17-28)35-22-20-34(21-23-35)31(36)24-30(26-12-5-2-6-13-26)27-14-7-3-8-15-27/h2-10,12-17,29-30,32H,11,18-25H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481458
(CHEMBL599015)Show SMILES Cc1ccc(C(N2CCN(CC2)C(=O)CC(c2ccccc2)c2ccccc2)c2ccccc2)c(C)c1 Show InChI InChI=1S/C34H36N2O/c1-26-18-19-31(27(2)24-26)34(30-16-10-5-11-17-30)36-22-20-35(21-23-36)33(37)25-32(28-12-6-3-7-13-28)29-14-8-4-9-15-29/h3-19,24,32,34H,20-23,25H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481471
(CHEMBL598990)Show SMILES FC(F)(F)c1ccccc1C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H31F3N2O/c34-33(35,36)30-19-11-10-18-28(30)32(27-16-8-3-9-17-27)38-22-20-37(21-23-38)31(39)24-29(25-12-4-1-5-13-25)26-14-6-2-7-15-26/h1-19,29,32H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481493
(CHEMBL597783)Show SMILES CN1CCC(CC1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C32H38FN3O/c1-34-18-16-28(17-19-34)32(27-12-14-29(33)15-13-27)36-22-20-35(21-23-36)31(37)24-30(25-8-4-2-5-9-25)26-10-6-3-7-11-26/h2-15,28,30,32H,16-24H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50461289
(MK-6721 | NMED-160 | NP-118809 | Z-160 | Z160)Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30,32H,21-25H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481456
(CHEMBL597756)Show SMILES Clc1cccc(c1)C(N1CCN(CC1)C(=O)NC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H30ClN3O/c32-28-18-10-17-27(23-28)30(26-15-8-3-9-16-26)34-19-21-35(22-20-34)31(36)33-29(24-11-4-1-5-12-24)25-13-6-2-7-14-25/h1-18,23,29-30H,19-22H2,(H,33,36) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481472
(CHEMBL597585)Show SMILES FC(F)(F)c1ccc(cc1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H31F3N2O/c34-33(35,36)29-18-16-28(17-19-29)32(27-14-8-3-9-15-27)38-22-20-37(21-23-38)31(39)24-30(25-10-4-1-5-11-25)26-12-6-2-7-13-26/h1-19,30,32H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481473
(CHEMBL608740)Show SMILES CN1CCC(CN2CCN(CC2)C(=O)CC(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C26H35N3O/c1-27-14-12-22(13-15-27)21-28-16-18-29(19-17-28)26(30)20-25(23-8-4-2-5-9-23)24-10-6-3-7-11-24/h2-11,22,25H,12-21H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481479
(CHEMBL598812)Show SMILES CN1CCC(CC1)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H39N3O/c1-33-19-17-29(18-20-33)32(28-15-9-4-10-16-28)35-23-21-34(22-24-35)31(36)25-30(26-11-5-2-6-12-26)27-13-7-3-8-14-27/h2-16,29-30,32H,17-25H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50481475
(CHEMBL598592)Show SMILES Clc1ccccc1C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H31ClN2O/c33-30-19-11-10-18-28(30)32(27-16-8-3-9-17-27)35-22-20-34(21-23-35)31(36)24-29(25-12-4-1-5-13-25)26-14-6-2-7-15-26/h1-19,29,32H,20-24H2 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.06E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Neuromed Pharmaceuticals Ltd
Curated by ChEMBL
| Assay Description
Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel... |
Bioorg Med Chem Lett 20: 1378-83 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR |
More data for this
Ligand-Target Pair | |
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